Brief Information of the Compound and Protein
Compound Name
N-benzyl-N-ethyl-5-methyl-1-(4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)-1H-pyrazole-4-carboxamide
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PubChem ID
CID: 137049186
Canonical SMILES
CCN(Cc1ccccc1)C(=O)c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1C
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Compound Formula C21H23N5O2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM