Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-chloro-6-methyl-2-[5-methyl-4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-pyrazol-1-yl]-3,4-dihydropyrimidin-4-one
    Show/Hide
 PubChem ID
CID: 137129894
Canonical SMILES
Cc1nc(-n2ncc(C(=O)N3CCc4ccccc4C3)c2C)[nH]c(=O)c1Cl
    Show/Hide
Compound Formula C19H18ClN5O2
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM