Brief Information of the Compound and Protein
Compound Name
(R)-tert-butyl methyl(1-(1-(4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)-1H-pyrazole-4-carbonyl)pyrrolidin-3-yl)carbamate
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PubChem ID
CID: 137049364
Canonical SMILES
CN(C(=O)OC(C)(C)C)[C@@H]1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2)C1
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Compound Formula C20H25N7O4
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM