Brief Information of the Compound and Protein
Compound Name
2-(4-(4-(benzo[d]thiazol-2-yl)piperidine-1-carbonyl)-5-methyl-1H-pyrazol-1-yl)-7-fluoropyrrolo[1,2-f][1,2,4]triazin-4(3H)-one
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PubChem ID
CID: 137049205
Canonical SMILES
Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)cnn1-c1nn2c(F)ccc2c(=O)[nH]1
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Compound Formula C23H20FN7O2S
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 87 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM