Brief Information of the Compound and Protein
Compound Name
2-(4-(4-(3,4-difluorophenylsulfonyl)piperidine-1-carbonyl)-5-methyl-1H-pyrazol-1-yl)thieno[3,2-d]pyrimidin-4(3H)-one
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PubChem ID
CID: 137049188
Canonical SMILES
Cc1c(C(=O)N2CCC(S(=O)(=O)c3ccc(F)c(F)c3)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1
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Compound Formula C22H19F2N5O4S2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM