Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-methyl-1-(4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)-N-(2,2,2-trifluoroethyl)-N-(3,3,3-trifluoropropyl)-1H-pyrazole-4-carboxamide
    Show/Hide
 PubChem ID
CID: 137049235
Canonical SMILES
Cc1c(C(=O)N(CCC(F)(F)F)CC(F)(F)F)cnn1-c1nc2c(c(=O)[nH]1)CCC2
    Show/Hide
Compound Formula C17H17F6N5O2
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM