Brief Information of the Compound and Protein
Compound Name
6-methyl-2-(5-methyl-4-(2-methylindoline-1-carbonyl)-1H-pyrazol-1-yl)pyrimidin-4(3H)-one
    Show/Hide
PubChem ID
CID: 137049037
Canonical SMILES
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3c4ccccc4CC3C)c2C)n1
    Show/Hide
Compound Formula C19H19N5O2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM