Brief Information of the Compound and Protein
Compound Name
methyl 3-(4-(5-methyl-1-(4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)-1H-pyrazole-4-carbonyl)piperazine-1-carbonyl)bicyclo[1.1.1]pentane-1-carboxylate
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PubChem ID
CID: 137129880
Canonical SMILES
COC(=O)C12CC(C(=O)N3CCN(C(=O)c4cnn(-c5nc6c(c(=O)[nH]5)CCC6)c4C)CC3)(C1)C2
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Compound Formula C24H28N6O5
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM