Brief Information of the Compound and Protein
Compound Name
2-(5-methyl-4-(2,6-diazaspiro[4.5]decane-2-carbonyl)-1H-pyrazol-1-yl)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
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PubChem ID
CID: 137129926
Canonical SMILES
Cc1c(C(=O)N2CCC3(CCCCN3)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2
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Compound Formula C20H26N6O2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM