Brief Information of the Compound and Protein
Compound Name
2-(3,5-dimethyl-4-(3-oxo-3-(pyrrolidin-1-yl)propyl)-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one
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PubChem ID
CID: 136253211
Canonical SMILES
Cc1cc(=O)[nH]c(-n2nc(C)c(CCC(=O)N3CCCC3)c2C)n1
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Compound Formula C17H23N5O2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 9000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 60 nM