Brief Information of the Compound and Protein
Compound Name
2-(4-(3-methoxypyrrolidine-1-carbonyl)-5-methyl-1H-pyrazol-1-yl)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
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PubChem ID
CID: 137049099
Canonical SMILES
COC1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)C1
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Compound Formula C17H21N5O3
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM