Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-2-(1-(1-(4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)-1H-pyrazole-4-carbonyl)piperidin-4-yl)propanenitrile
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 PubChem ID
CID: 137049176
Canonical SMILES
CC(C)(C#N)C1CCN(C(=O)c2cnn(-c3nc4ccsc4c(=O)[nH]3)c2)CC1
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Compound Formula C19H20N6O2S
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 62 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM