Brief Information of the Compound and Protein
Compound Name
2-(3,5-dimethyl-4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-pyrazol-1-yl)thieno[3,2-d]pyrimidin-4(3H)-one
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PubChem ID
CID: 137049163
Canonical SMILES
Cc1nn(-c2nc3ccsc3c(=O)[nH]2)c(C)c1C(=O)N1CCc2ccccc2C1
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Compound Formula C21H19N5O2S
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM