Brief Information of the Compound and Protein
Compound Name
N,5-dimethyl-1-(4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)-N-(quinolin-6-ylmethyl)-1H-pyrazole-4-carboxamide
    Show/Hide
PubChem ID
CID: 137049211
Canonical SMILES
Cc1c(C(=O)N(C)Cc2ccc3ncccc3c2)cnn1-c1nc2c(c(=O)[nH]1)CCC2
    Show/Hide
Compound Formula C23H22N6O2
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM