Brief Information of the Compound and Protein
Compound Name
2-(4-(4-(benzo[d]thiazol-2-yl)piperidine-1-carbonyl)-5-cyclopropyl-1H-pyrazol-1-yl)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
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PubChem ID
CID: 137049346
Canonical SMILES
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1C1CC1)N1CCC(c2nc3ccccc3s2)CC1
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Compound Formula C26H26N6O2S
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 84 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM