Brief Information of the Compound and Protein
Compound Name
2-(4-[[4-(trifluoromethyl)piperidin-1-yl]sulfonyl]pyridin-2-yl)-3H,4H,5H,6H,7H-cyclopenta[d]pyrimidin-4-one
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PubChem ID
CID: 137129921
Canonical SMILES
O=c1[nH]c(-c2cc(S(=O)(=O)N3CCC(C(F)(F)F)CC3)ccn2)nc2c1CCC2
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Compound Formula C18H19F3N4O3S
Compound Structure
Protein Name
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2) Homo sapiens (Human)  1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 300 nM