Brief Information of the Compound and Protein
Compound Name
(3S,6S,11aS)-7,8,10-trimethoxy-9-methyl-6-[(E)-2-phenylethenyl]-3-[(2,4,5-trimethoxy-3-methylphenyl)methyl]-3,6,11,11a-tetrahydro-2H-pyrazino[1,2-b]isoquinoline-1,4-dione
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PubChem ID
CID: 155558303
Canonical SMILES
COc1cc(C[C@@H]2NC(=O)[C@@H]3Cc4c(OC)c(C)c(OC)c(OC)c4[C@H](\C=C\c4ccccc4)N3C2=O)c(OC)c(C)c1OC
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Compound Formula C35H40N2O8
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 20800 nM
   TI
   LI
   LO
   TS
2
IC50 = 3200 nM
   TI
   LI
   LO
   TS