Brief Information of the Compound and Protein
Compound Name
(3Z,6R,11aS)-3-[(3,4-dimethoxyphenyl)methylidene]-8,9-dimethoxy-6-phenyl-11,11a-dihydro-6H-pyrazino[1,2-b]isoquinoline-1,4-dione
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PubChem ID
CID: 155567112
Canonical SMILES
COc1ccc(\C=C2/NC(=O)[C@@H]3Cc4cc(OC)c(OC)cc4[C@H](N3C2=O)c2ccccc2)cc1OC
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Compound Formula C29H28N2O6
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 15900 nM
   TI
   LI
   LO
   TS
2
IC50 = 12800 nM
   TI
   LI
   LO
   TS