Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3Z,6R,11aS)-3-[(3,4-dimethoxyphenyl)methylidene]-8,9-dimethoxy-6-phenyl-11,11a-dihydro-6H-pyrazino[1,2-b]isoquinoline-1,4-dione
    Show/Hide
 PubChem ID
CID: 155567112
Canonical SMILES
COc1ccc(\C=C2/NC(=O)[C@@H]3Cc4cc(OC)c(OC)cc4[C@H](N3C2=O)c2ccccc2)cc1OC
    Show/Hide
Compound Formula C29H28N2O6
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 15900 nM
   TI
   LI
   LO
   TS
2
IC50 = 12800 nM
   TI
   LI
   LO
   TS