Brief Information of the Compound and Protein
Compound Name
INCB-018424
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PubChem ID
CID: 25126798
SID: 81071277
Canonical SMILES
N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
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Compound Formula C17H18N6
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
Q62120
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
EC50 = 186 nM
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