Brief Information of the Compound and Protein
Compound Name
N-(1-(4-(3-(3-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)-1-ethylpiperidine-4-carboxamide
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PubChem ID
CID: 126738197
Canonical SMILES
CCN1CCC(C(=O)NC2CCN(c3ccc(NC(=O)Nc4cccc(Oc5ccnc6cc(OC)c(OC)cc56)c4)cc3C(F)(F)F)CC2)CC1
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Compound Formula C38H43F3N6O5
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
GI50 = 39 nM
   TI
   LI
   LO
   TS
2
GI50 = 87 nM
   TI
   LI
   LO
   TS