Brief Information of the Compound and Protein
Compound Name
N-(3-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-(4-propionamidopiperidin-1-yl)-3-(trifluoromethyl)phenyl)-cyclopropane 1,1-Dicarboxamide
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PubChem ID
CID: 126738320
Canonical SMILES
CCC(=O)NC1CCN(c2ccc(NC(=O)C3(C(=O)Nc4cccc(Oc5ccnc6cc(OC)c(OC)cc56)c4)CC3)cc2C(F)(F)F)CC1
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Compound Formula C37H38F3N5O6
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS