Brief Information of the Compound and Protein
Compound Name
1-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-3-[4-(1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)phenyl]urea
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PubChem ID
CID: 118489449
Canonical SMILES
Cn1nc(cc1NC(=O)Nc1ccc(Oc2ncnc3[nH]ncc23)cc1)C(F)(F)F
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Compound Formula C17H13F3N8O2
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 38 nM
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