Brief Information of the Compound and Protein
Compound Name
2-(4-acetylpiperazin-1-yl)-4-[[1-(4-chlorophenyl)-2-methylpropan-2-yl]amino]-6-propan-2-yl-5H-pyrrolo[3,4-d]pyrimidin-7-one
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PubChem ID
CID: 25122581
SID: 56446781
Canonical SMILES
CC(C)N1Cc2c(nc(nc2NC(C)(C)Cc2ccc(Cl)cc2)N2CCN(CC2)C(C)=O)C1=O
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Compound Formula C25H33ClN6O2
Compound Structure
Protein Name
P2X purinoceptor 3
Protein Classification
Ion channel
>
Ligand-gated ion channel
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P2X receptor
Uniprot ID
P56373
Gene Name
P2RX3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000088 Flp-In-293 Homo sapiens (Human)  1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CL000761 RLE Rattus norvegicus (Rat)  1
1
IC50 = 61 nM
   TI
   LI
   LO
   TS