Brief Information of the Compound and Protein
Compound Name
6-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl]-N-(2-morpholin-4-ylethyl)-1,3-benzothiazol-2-amine
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PubChem ID
CID: 42598657
SID: 74370467
Canonical SMILES
Fc1ccc(cc1)-c1ccc2nnc(Sc3ccc4nc(NCCN5CCOCC5)sc4c3)n2n1
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Compound Formula C24H22FN7OS2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000413 MKN45 Homo sapiens (Human)  1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM
2 IC50 = 455 nM
3 IC50 = 835 nM
4 IC50 > 10000 nM