Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-(1-ethylpiperidin-4-yl)ethyl]-3-[6-[(6-thiophen-2-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)sulfanyl]-1,3-benzothiazol-2-yl]urea
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 PubChem ID
CID: 137348420
Canonical SMILES
CCN1CCC(CCNC(=O)Nc2nc3ccc(Sc4nnc5ccc(nn45)-c4cccs4)cc3s2)CC1
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Compound Formula C26H28N8OS3
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000413 MKN45
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM
2 IC50 = 23 nM