Brief Information of the Compound and Protein
Compound Name
2-nitro-4-[(2-phenylquinazolin-4-yl)amino]phenol
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PubChem ID
CID: 132547158
Canonical SMILES
Oc1ccc(Nc2nc(nc3ccccc23)-c2ccccc2)cc1[N+]([O-])=O
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Compound Formula C20H14N4O3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  6
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
2
EC50 = 130 nM
   TI
   LI
   LO
   TS
3
GI50 = 68.4 nM
   TI
   LI
   LO
   TS
4
IC50 = 80 nM
   TI
   LI
   LO
   TS
5
IC50 = 81.1 nM
   TI
   LI
   LO
   TS
6
IC50 = 113 nM
   TI
   LI
   LO
   TS