Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[(3R)-3,7-dimethyl-3-(methylsulfonylmethyl)-2H-1,4-benzoxazine-4-carbonyl]-4H-1,4-benzoxazin-3-one
    Show/Hide
 PubChem ID
CID: 155556878
Canonical SMILES
Cc1ccc2N(C(=O)c3ccc4OCC(=O)Nc4c3)[C@@](C)(CS(C)(=O)=O)COc2c1
    Show/Hide
Compound Formula C21H22N2O6S
Compound Structure
Protein Name
 Protein Info 
Mineralocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 2
Uniprot ID
P08235
Gene Name
NR3C2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000952 UAS-MR-bla HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 63.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 15.85 nM