Brief Information of the Compound and Protein
Compound Name
N-(1-oxo-3H-2-benzofuran-5-yl)-2-[3-[(E)-3-phenylprop-2-enoyl]phenoxy]acetamide
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PubChem ID
CID: 145982128
Canonical SMILES
O=C(COc1cccc(c1)C(=O)\C=C\c1ccccc1)Nc1ccc2C(=O)OCc2c1
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Compound Formula C25H19NO5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
EC50 = 1170 nM
   TI
   LI
   LO
   TS
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 6080 nM
   TI
   LI
   LO
   TS