Brief Information of the Compound and Protein
Compound Name
2-[3-(4-methoxyphenyl)-4-oxochromen-2-yl]oxy-N-naphthalen-1-ylacetamide
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PubChem ID
CID: 155537197
Canonical SMILES
COc1ccc(cc1)-c1c(OCC(=O)Nc2cccc3ccccc23)oc2ccccc2c1=O
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Compound Formula C28H21NO5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
EC50 = 793 nM
   TI
   LI
   LO
   TS
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 5090 nM
   TI
   LI
   LO
   TS