Brief Information of the Compound and Protein
Compound Name
2-[4-[(E)-3-(2,6-difluorophenyl)prop-2-enoyl]phenoxy]-N-(3,4-dimethoxyphenyl)acetamide
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PubChem ID
CID: 145987093
Canonical SMILES
COc1ccc(NC(=O)COc2ccc(cc2)C(=O)\C=C\c2c(F)cccc2F)cc1OC
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Compound Formula C25H21F2NO5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
EC50 = 448 nM
   TI
   LI
   LO
   TS
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 6110 nM
   TI
   LI
   LO
   TS