Brief Information of the Compound and Protein
Compound Name
N-(3,4-dimethoxyphenyl)-2-[4-[(E)-3-(3-methoxyphenyl)prop-2-enoyl]phenoxy]acetamide
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PubChem ID
CID: 145986566
Canonical SMILES
COc1cccc(\C=C\C(=O)c2ccc(OCC(=O)Nc3ccc(OC)c(OC)c3)cc2)c1
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Compound Formula C26H25NO6
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
EC50 = 1390 nM
   TI
   LI
   LO
   TS
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 3580 nM
   TI
   LI
   LO
   TS