Brief Information of the Compound and Protein
Compound Name
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]phenoxy]acetamide
    Show/Hide
PubChem ID
CID: 145979318
Canonical SMILES
COc1cc(\C=C\C(=O)c2ccc(OCC(=O)NCc3ccc4OCOc4c3)cc2)cc(OC)c1OC
    Show/Hide
Compound Formula C28H27NO8
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
EC50 = 989 nM
   TI
   LI
   LO
   TS
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 6890 nM
   TI
   LI
   LO
   TS