Brief Information of the Compound and Protein
Compound Name
2-(5-((2-amino-4-cyclopropylpyrimidin-5-yl)methoxy)-2-bromo-4-hydroxybenzylidene)thieno[2,3-b]pyridin-3(2H)-one
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PubChem ID
CID: 140897160
Canonical SMILES
Nc1ncc(COc2cc(/C=C3\Sc4ncccc4C3=O)c(Br)cc2O)c(C2CC2)n1
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Compound Formula C22H17BrN4O3S
Compound Structure
Protein Name
Cyclic GMP-AMP synthase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8N884
Gene Name
CGAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 2500 nM
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