Brief Information of the Compound and Protein
Compound Name
5-(4-chlorophenyl)-2-pyrrolidin-1-yl-3H-pyrido[2,3-d]pyrimidin-4-one
    Show/Hide
PubChem ID
CID: 135646528
Canonical SMILES
Clc1ccc(cc1)-c1ccnc2nc([nH]c(=O)c12)N1CCCC1
    Show/Hide
Compound Formula C17H15ClN4O
Compound Structure
Protein Name
Adenosine receptor A1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P30542
Gene Name
ADORA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 776.25 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1862.09 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1479.11 nM