Brief Information of the Compound and Protein
Compound Name
 Compound Info 
RICOLINOSTAT
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 PubChem ID
CID: 53340666
SID: 125005606
Canonical SMILES
ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N(c1ccccc1)c1ccccc1
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Compound Formula C24H27N5O3
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 6
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class IIb
Uniprot ID
Q9UBN7
Gene Name
HDAC6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  6
1
IC50 = 2.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.59 nM
   TI
   LI
   LO
   TS
3
IC50 = 4.7 nM
   TI
   LI
   LO
   TS
4
IC50 = 5 nM
   TI
   LI
   LO
   TS
5
IC50 = 9 nM
   TI
   LI
   LO
   TS
6
IC50 = 12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.7 nM
2 IC50 = 5 nM
3 IC50 = 6.8 nM
4 IC50 = 7 nM
5 IC50 = 9 nM
6 IC50 = 17 nM
7 IC50 = 17.9 nM
8 IC50 = 20 nM
9 IC50 = 27 nM
10 IC50 = 29 nM
11 IC50 = 2600 nM
12 Ki = 1 nM