Brief Information of the Compound and Protein
Compound Name
N,N-bis(pyridin-2-ylmethyl)-6-thiophen-3-yl-2-(trifluoromethyl)pyrimidin-4-amine
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PubChem ID
CID: 155514726
Canonical SMILES
FC(F)(F)c1nc(cc(n1)-c1ccsc1)N(Cc1ccccn1)Cc1ccccn1
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Compound Formula C21H16F3N5S
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 2500 nM
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