Brief Information of the Compound and Protein
Compound Name
6-(2-methoxypyridin-3-yl)-4-N,4-N-bis(pyridin-2-ylmethyl)pyrimidine-2,4-diamine
    Show/Hide
PubChem ID
CID: 155566198
Canonical SMILES
COc1ncccc1-c1cc(nc(N)n1)N(Cc1ccccn1)Cc1ccccn1
    Show/Hide
Compound Formula C22H21N7O
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Nicotinic acetylcholine receptor
>
Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 230 nM
   TI
   LI
   LO
   TS