Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10005782, Compound 151
    Show/Hide
 PubChem ID
CID: 136983741
Canonical SMILES
NC(=O)c1c2NCCC(c3ccccc3NC(=O)C=C)n2nc1-c1ccc(F)cc1
    Show/Hide
Compound Formula C22H20FN5O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.5 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.9 nM