Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10005782, Compound 14
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 PubChem ID
CID: 136983730
Canonical SMILES
CN(C(=O)C=C)c1ccccc1C1CCNc2c(C(N)=O)c(nn12)-c1ccc(Oc2ccccc2)cc1
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Compound Formula C29H27N5O3
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 232.6 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 4.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.7 nM