Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ethyl (3E)-3-[3-(6-methylpyridin-2-yl)prop-2-ynylidene]pyrrolidine-1-carboxylate
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 PubChem ID
CID: 155555556
Canonical SMILES
CCOC(=O)N1CC\C(C1)=C/C#Cc1cccc(C)n1
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Compound Formula C16H18N2O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
2
IC50 = 4.1 nM
   TI
   LI
   LO
   TS
3
IC50 > 20000 nM
   TI
   LI
   LO
   TS
4
Ki = 3.5 nM
   TI
   LI
   LO
   TS