Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ethyl 3-[3-(6-methylpyridin-2-yl)prop-2-ynylidene]azetidine-1-carboxylate
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 PubChem ID
CID: 155530468
Canonical SMILES
CCOC(=O)N1CC(C1)=CC#Cc1cccc(C)n1
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Compound Formula C15H16N2O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 117 nM
   TI
   LI
   LO
   TS
2
Ki = 38.3 nM
   TI
   LI
   LO
   TS