Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[3-[1-(3-bromophenyl)sulfonylpiperidin-4-ylidene]prop-1-ynyl]-6-methylpyridine
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 PubChem ID
CID: 57575026
Canonical SMILES
Cc1cccc(n1)C#CC=C1CCN(CC1)S(=O)(=O)c1cccc(Br)c1
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Compound Formula C20H19BrN2O2S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 89.9 nM
   TI
   LI
   LO
   TS
2
Ki = 18.2 nM
   TI
   LI
   LO
   TS