Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-6-[3-[1-(4-methylphenyl)sulfonylpiperidin-4-ylidene]prop-1-ynyl]pyridine
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 PubChem ID
CID: 87550393
Canonical SMILES
Cc1ccc(cc1)S(=O)(=O)N1CCC(CC1)=CC#Cc1cccc(C)n1
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Compound Formula C21H22N2O2S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 43.8 nM
   TI
   LI
   LO
   TS
2
Ki = 2.7 nM
   TI
   LI
   LO
   TS