Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ethyl 6-[3-(6-methylpyridin-2-yl)prop-2-ynylidene]-2-azaspiro[3.3]heptane-2-carboxylate
    Show/Hide
 PubChem ID
CID: 155554969
Canonical SMILES
CCOC(=O)N1CC2(C1)CC(C2)=CC#Cc1cccc(C)n1
    Show/Hide
Compound Formula C18H20N2O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P23385
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS