Brief Information of the Compound and Protein
Compound Name
2-(3,5-difluorophenyl)-1-[4-[3-(6-methylpyridin-2-yl)prop-2-ynylidene]piperidin-1-yl]ethanone
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PubChem ID
CID: 57574885
Canonical SMILES
Cc1cccc(n1)C#CC=C1CCN(CC1)C(=O)Cc1cc(F)cc(F)c1
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Compound Formula C22H20F2N2O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 194 nM
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