Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3,3-dimethyl-1-[4-[3-(6-methylpyridin-2-yl)prop-2-ynylidene]piperidin-1-yl]butan-1-one
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 PubChem ID
CID: 57575054
Canonical SMILES
Cc1cccc(n1)C#CC=C1CCN(CC1)C(=O)CC(C)(C)C
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Compound Formula C20H26N2O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 48.2 nM
   TI
   LI
   LO
   TS