Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3E)-N-methyl-3-[3-(6-methylpyridin-2-yl)prop-2-ynylidene]-N-propan-2-ylpyrrolidine-1-carboxamide
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 PubChem ID
CID: 155530190
Canonical SMILES
CC(C)N(C)C(=O)N1CC\C(C1)=C/C#Cc1cccc(C)n1
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Compound Formula C18H23N3O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000308 T-REx-CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 15.1 nM
   TI
   LI
   LO
   TS
2
Ki = 8.6 nM
   TI
   LI
   LO
   TS