Brief Information of the Compound and Protein
Compound Name
N-((R)-1-((S)-3-(4-methoxyphenyl)-1-((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-yl)-3-methyl-1H-indene-2-carboxamide
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PubChem ID
CID: 117611892
Canonical SMILES
COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)C2=C(C)c3ccccc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1
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Compound Formula C36H39N3O6
Compound Structure
Protein Name
Proteasome subunit beta type-8
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P28062
Gene Name
PSMB8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  1
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
CL000174 Raji Homo sapiens (Human)  1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS