Brief Information of the Compound and Protein
Compound Name
3-(3-chloro-4-fluorophenyl)-1-[(1S,5S)-5-(4-methylsulfonylphenyl)-2-bicyclo[3.1.0]hexanyl]-1-(2-pyridin-2-ylethyl)urea
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PubChem ID
CID: 155541584
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)[C@@]12C[C@@H]1C(CC2)N(CCc1ccccn1)C(=O)Nc1ccc(F)c(Cl)c1
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Compound Formula C27H27ClFN3O3S
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS