Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(1S,4R,6R)-4-[(5-chloro-6-fluoro-1H-benzimidazol-2-yl)-[3-(4-methylpiperazin-1-yl)propyl]amino]-1-bicyclo[4.1.0]heptanyl]benzonitrile
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 PubChem ID
CID: 155531314
Canonical SMILES
CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@@H]3C2)c2ccc(cc2)C#N)c2nc3cc(F)c(Cl)cc3[nH]2)CC1
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Compound Formula C29H34ClFN6
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4.9 nM
   TI
   LI
   LO
   TS